Dilantin Facies: A Summary

Dilantin, or phenytoin, is an anticonvulsant medication commonly used to manage seizures. One of the notable side effects associated with long-term use of phenytoin is the development of "Dilantin facies." This term refers to distinctive facial changes that can occur in patients receiving phenytoin therapy, characterized by the coarsening of facial features, gingival hyperplasia (overgrown gums), and sometimes hirsutism (excessive hair growth) (source: PubMed).

The phenomenon of Dilantin facies is linked to the drug's interaction with specific fibroblasts in the body, leading to the overgrowth of gum tissue and changes in facial appearance. The manifestation of these side effects can be quite pronounced in some patients, often impacting their overall appearance and self-esteem (source: LWW).

In addition to gingival hyperplasia and coarse facies, patients on phenytoin may experience a variety of other skin-related side effects. Research has shown that more than 50% of patients exhibit notable changes in facial features, which may include various skin conditions such as acne (source: ScienceDirect).

Patients and healthcare providers need to be aware of these potential side effects when prescribing phenytoin to manage seizures. Being vigilant can help mitigate the impact of these dermatological changes, which may be significant enough to warrant changing the patient's treatment plan (source: PubMed).

In summary, Dilantin facies is a clinical manifestation associated with phenytoin therapy, illustrating the importance of monitoring patients for cosmetic and dermatological effects while treating them for their underlying neurological conditions.

Sources

Impact of phenytoin therapy on the skin and skin disease - PubMedPhenytoin induced coarse facies, gum hypertrophy and... - LWWPhenytoin in cutaneous medicine: its uses, mechanisms and side ...Cosmetic adverse effects of antiseizure medications; A systematic ...Recognising phenytoin therapy as a cause of thickening of ... - jprasPhenytoin in cutaneous medicine: Its uses and side effectsDilantin: Uses, Dosage, Side Effects & Interactions - Drugs.com

Related Questions

What are the facial features of phenytoin patients?

What effect does phenytoin have on the face?

What is the major side effect of Dilantin?

How does phenytoin cause hirsutism?